In 2029, no mutants have been born in 25 years, and an aging Logan suffers as his healing ability is failing. Working as a limo driver in El Paso, Texas, under his birth name James Howlett, he and mutant tracker Caliban care for 90-year-old Charles Xavier, Logan's mentor and founder of the X-Men, in an abandoned smelting plant in northern Mexico. Xavier has developed dementia that causes him to have destructive seizures; it is alluded that one year prior, one such seizure released a powerful wave of telepathy that injured over six hundred people and killed seven people, including several X-Men.

Logan reluctantly agrees to escort Gabriela Lopez, a former nurse for biotechnology corporation Alkali-Transigen, and a young girl called Laura to Eden, a refuge "up north" across the border. Later finding Gabriela dead, Logan is confronted at his Mexican hideout by her killer Donald Pierce, who is Transigen's cyborg chief of security. Pierce is looking for Laura, who has stowed away in Logan's limo and has powers similar to his. She, Logan, and Xavier escape Pierce and his Reavers, but Caliban is tortured into tracking Laura.

A video on Gabriela's cellphone shows that Transigen created Laura and other children from mutant DNA to become weapons; Laura was created from Logan's DNA. As they proved difficult to control and Transigen found an alternative, the children were to be killed, but Gabriela and other nurses helped some escape. In Oklahoma City, Logan discovers that Eden appears in Laura's X-Men comic and tells her it is fictional. The Reavers arrive, but Xavier has a seizure which incapacitates everyone except Logan and Laura, who kill the attackers and inject Xavier with his medication. As they flee, Dr. Zander Rice (the head of Transigen) arrives to help Pierce.

Logan, Laura, and Xavier help farmer Will Munson and his family after a traffic incident, accepting an offer of dinner at their home, where Logan drives off enforcers from a corporate farm. Rice unleashes X-24, a clone of Logan in his prime and his alternative to the child program, who murders Will's family and Xavier, stabbing Will and capturing Laura. He also kills the enforcers, who mistake him as Logan and try to kill him. Caliban sets off grenades, killing himself and several Reavers, but only injuring Pierce. Logan is outmatched by X-24, but Will pins X-24 with his truck and shoots him three times with a shotgun before dying from his injuries. Logan and Laura escape with Xavier's body.

After burying Xavier, Logan passes out. Laura takes him to a doctor and persuades him to prove that the site in North Dakota is not Eden. There, they find Rictor and other Transigen children preparing to cross into Canada. Laura finds an adamantium bullet that Logan has kept since his escape from the Weapon X facility, which he once considered using to commit suicide. Logan decides that his job is done and chooses not to accompany them, to Laura's dismay.

When the Reavers ambush the children, Logan takes an overdose of a serum given to him by Rictor that temporarily enhances his healing abilities and boosts his strength. With Laura's help, he slaughters most of the Reavers before the serum wears off. As Pierce holds Rictor at gunpoint Rice tells Logan, who killed Rice's father years ago at the Weapon X facility, that no new mutants have been born due to genetically engineered crops created by Transigen and distributed through the world's food supply. Logan, having found a gun, shoots Rice and injures Pierce. X-24, enraged by Rice's death, fights Logan as the children combine their powers to kill Pierce and the remaining Reavers. Rictor uses his powers to flip a truck onto X-24, but he frees himself and impales Logan on a large tree branch. Laura loads Logan's revolver with the adamantium bullet and shoots X-24 in the head, killing him.

Near death, Logan tells Laura not to become the weapon that she was made to be, and after she tearfully acknowledges him as her father, he dies peacefully in her arms. Laura and the children bury Logan, and Laura tilts the cross on his grave marker to create an X, honoring him as the last of the X-Men, before she and the children depart for the Canadian border.

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(https://en.wikipedia.org/wiki/Logan_(film))